Please use this identifier to cite or link to this item: http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/5782
Title: Synthesis and biological activity of some benzofuro[3,2-d]pyrimidines
Authors: Bodke, Y
Sangapure, SS
Issue Date: 2003
Publisher: INDIAN CHEMICAL SOC
Citation: JOURNAL OF THE INDIAN CHEMICAL SOCIETY , Vol. 80 , 3 , p. 187 - 189
Abstract: The condensation of ethyl 3-amino-2-benzofuran carboxylate (1) with phenyl isocyanate gave 3-phenylureido-2-benzofuran carboxylate (2), which upon treatment with phosphorus oxychloride gave 2-chloro-3-phenyl-3,4-dihydro-4-oxobenzofuro[3,2-d]pyrimidine (4). The reaction of 4 with alicyclic amines like piperidine and morpholine yielded 2-piperidino/morpholino compounds (5a and 5b, respectively). 2-Hydrazino-3-phenyl-3,4-dihydro-4-oxobenzofuro[3,-d]pyrimidine (6) obtained from 4 was subjected to reactions with different reagents. All compounds were screened for their antibacterial and antifungal activities.
URI: http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/5782
Appears in Collections:1. Journal Articles

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