Synthesis, characterization and biological studies of cobalt(II) and nickel(II) complexes with new Schiff bases

Abstract

Complexes of CoII and NiII with new Schiff bases derived from 4-amino-5-sulfanyl-1,2,4-triazoles and glyoxal, biacetyl or benzil have been prepared. All have the stoichiometry ML(H2O)2, with L coordination via the two imine nitrogens and two thiolato sulfurs in an overall octahedral geometry. Some of the complexes were screened for their antibacterial and antifungal activity, and one representative CoII complex was evaluated for oxytocic activity. © 1997 Chapman & Hall.