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Title: | Synthesis of some new pyrazolines and isoxazoles carrying 4-methylthiophenyl moiety as potential analgesic and anti-inflammatory agents |
Authors: | Karabasanagouda, T Adhikari, AV Girisha, M |
Keywords: | 4-Acetylthioanisole arylaldehydes propenones pyrazolines isoxazoles analgesic anti-inflammatory activity |
Issue Date: | 2009 |
Publisher: | NATL INST SCIENCE COMMUNICATION & INFORMATION RESOURCES-NISCAIR |
Citation: | INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY , Vol. 48 , 3 , p. 430 - 437 |
Abstract: | A series of new pyrazolines 3a-m and isoxazoles 4a-k haw been synthesized from 4-acetylthioanisole, 1 with aryl aldehydes through alpha, beta-unsaturated ketones. The structures of the newly synthesized compounds have been confirmed oil the basis of elemental analysis and spectral studies. The newly synthesized title compounds have been tested for their analgesic and anti-inflammatory activity. Some of the compounds exhibited encouraging results. |
URI: | http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/5148 |
Appears in Collections: | 1. Journal Articles |
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