Synthesis Antioxidant and Antimicrobial Activities of N-[(5 '-Substituted 2 '-phenyl-1H-indol-3 '-yl)methylene]-5-(pyridin-4-yl)-1,3,4-oxadiazol-2-amines

Abstract

The main aim of the present study was to develop antimicrobial and antioxidant compounds. As a part of systematic investigation, several new compounds 3a-c, 4a-c, and 5a-f were synthesized and screened for their biological activities. Compound 5f showed good zone of inhibition versus E. coli, S. aureus, and K. pneumoniae, whereas the compound 3a showed promising radical scavenging activity, ferric ions (Fe3+) reducing antioxidant power, and ferrous ions (Fe2+) metal chelating activity.