Synthesis, Physico-Chemical and Antimicrobial Studies of N1',N6'-bis((2- hydroxyquinolin-3-yl)methylene)adipohydrazide and their metal (II) complexes

Abstract

The Cu(II), Co(II), Ni(II), Mn(II), Zn(II), Cd(II), and Hg(II), complexes of Schiff base N1',N6'- bis((2-hydroxyquinolin-3-yl)methylene)adipohydrazide has been synthesized and characterized by various spectral techniques. The complexes were prepared by reacting the ligand and metal chloride of Cu(II), Co(II), Ni(II), Mn(II), Zn(II), Cd(II), and Hg(II), in ethanol to get a series of mononuclear complexes. The complexes were characterized by CHN analysis, conductivity measurements, magnetic susceptibility, IR, NMR, ESR, UV-Vis and X-ray Powder diffraction studies. By these spectral studies it is found that Cu(II), Co(II), Ni(II), Mn(II), Zn(II), Cd(II), and Hg(II) complexes have exhibited octahedral geometry The ligand and its metal complexes have been screened for their antimicrobial activities. The prepared ligand shows low activity and its metal complexes shows moderate to good activity.