Phytochemical screening and antimicrobial activities of Ficus glomerata Roxb fruit extracts

Abstract

Objective: The present study designed to evaluate the antibacterial activities of Ficus glomerata fruit extracts Method: Dried fruit powder of Ficus glomerata extracted in Soxhlet apparatus using the solvents petroleum ether, chloroform, methanol and water. Preliminary phytochemical and Physico- chemical studies were carried out. The antimicrobial activity of the fruit extract against pathogenic strains evaluated based on the inhibition zone using well diffusion assay, minimum inhibition concentration (MIC) is studied using micro dilution method. Results: The qualitative phytochemical tests exhibited the presence of common bioactive compounds including alkaloids, terpenoids, flavonoids, saponins and oils as major active constituents. Among the studies conducted against pathogenic microorganisms, the chloroform extract has shown weak activity. Whereas aqueous extract has shown moderate activity and methanolic extract has shown significantly good activity when compared to standard chemotherapeutic agent streptomycin sulphate. Conclusion: Based on the results we conclude that the Ficus glomerata is rich in bioactive principles and exhibits antimicrobial activity against pathogens.