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Title: | Synthesis of Some Indolyl Derivatives under Solvent Free Conditions, Their Cytotoxicity, and DNA Cleavage Studies |
Authors: | Rathod, AS Biradar, JS |
Keywords: | indole pyran dimedone thiobarbutiric and barbutiric acid MW-assisted green synthesis anticancer activity DNA cleavage |
Issue Date: | 2020 |
Publisher: | MAIK NAUKA/INTERPERIODICA/SPRINGER |
Citation: | RUSSIAN JOURNAL OF GENERAL CHEMISTRY , Vol. 90 , 1 , p. 135 - 141 |
Abstract: | A one-pot, rapid, facile, green, and efficient method of synthesis of pyran fused indolyl and 1,3-dicarbonyl analogs has been carried out under the conventional and also solvent-free conditions involving MW irradiation. The structures of products have been confirmed by spectral data. All products have been tested for DNA cleavage and in vitro cytotoxicity against three tumor cell lines. Some products are characterized by high activity. |
URI: | 10.1134/S1070363220010211 http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/4304 |
Appears in Collections: | 1. Journal Articles |
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