Please use this identifier to cite or link to this item: http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/4304
Title: Synthesis of Some Indolyl Derivatives under Solvent Free Conditions, Their Cytotoxicity, and DNA Cleavage Studies
Authors: Rathod, AS
Biradar, JS
Keywords: indole
pyran
dimedone
thiobarbutiric and barbutiric acid
MW-assisted
green synthesis
anticancer activity
DNA cleavage
Issue Date: 2020
Publisher: MAIK NAUKA/INTERPERIODICA/SPRINGER
Citation: RUSSIAN JOURNAL OF GENERAL CHEMISTRY , Vol. 90 , 1 , p. 135 - 141
Abstract: A one-pot, rapid, facile, green, and efficient method of synthesis of pyran fused indolyl and 1,3-dicarbonyl analogs has been carried out under the conventional and also solvent-free conditions involving MW irradiation. The structures of products have been confirmed by spectral data. All products have been tested for DNA cleavage and in vitro cytotoxicity against three tumor cell lines. Some products are characterized by high activity.
URI: 10.1134/S1070363220010211
http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/4304
Appears in Collections:1. Journal Articles

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