Please use this identifier to cite or link to this item: http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/4281
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dc.contributor.authorVerma V.A
dc.contributor.authorSaundane A.R.
dc.date.accessioned2020-06-12T15:02:55Z-
dc.date.available2020-06-12T15:02:55Z-
dc.date.issued2019
dc.identifier.citationPolycyclic Aromatic Compounds , Vol. , , p. -en_US
dc.identifier.uri10.1080/10406638.2019.1628782
dc.identifier.urihttp://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/4281-
dc.description.abstractAs a part of systematic investigation, a novel series of 5-(8-Substituted-11H-indolo[3,2-c] isoquinolin-5-ylthio)-N-{(5-substituted-2-phenyl-1H-indol-3-yl)methylene)-1?,3?,4?-oxadiazol-2-amine analogs were synthesized and appraised for their in vitro antimicrobial, antioxidant, anti-tuberculosis and anticancer activity against three tumor cell lines. Amidst the compounds tested 6a has demonstrated intense antibacterial and radical scavenging activities. Compound 7a revealed efficient to fantabulous antifungal activity. It is worth noting that compound 6g was most active antituberculosis agent against H37Rv strain Mycobacterium tuberculosis. In case of anticancer activity compounds 6e and 8e against all the three tumor cell lines manifested remarkable cytotoxic activity. Ferrous ions (Fe3+) reducing antioxidant power was shown by compound 6e. © 2019, © 2019 Taylor & Francis Group, LLC.en_US
dc.publisherTaylor and Francis Inc.
dc.subjectAzetidinone
dc.subjectindolo[3,2-c]isoquinoline
dc.subjectoxadiazole
dc.subjectthiazolidinone
dc.titleSynthesis of Some Novel 5-(8-Substituted-11H-Indolo[3,2-c]Isoquinolin-5-ylthio)-1,3,4-Oxadiazol-2-Amines Bearing Thiazolidinones and Azetidinones as Potential Antimicrobial, Antioxidant, Antituberculosis, and Anticancer Agentsen_US
dc.typeArticle
Appears in Collections:1. Journal Articles

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