Please use this identifier to cite or link to this item: http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/4227
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dc.contributor.authorManjunath A
dc.contributor.authorKerur B.R.
dc.date.accessioned2020-06-12T15:02:45Z-
dc.date.available2020-06-12T15:02:45Z-
dc.date.issued2013
dc.identifier.citationResearch Journal of Pharmaceutical, Biological and Chemical Sciences , Vol. 4 , 4 , p. 1180 - 1190en_US
dc.identifier.urihttp://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/4227-
dc.description.abstractAnalysis is a critical and integral part of the pharma business. Its only upon clearance of products on the analysis can the products be even released into the market. Therefore, analytical methods as well as the involved analytical tools assume prime importance for the qualitative and quantitative test. Hence a non-destructive technique has been developed for the rapid quantitative analysis of active and inactive pharmaceutical ingredients present in the Alprazolam, Famotidine and Diclofenac sodium drug samples by determining mass attenuation coefficient in the low energy (X-ray) region. The x-ray mass attenuation coefficients were studied for above said drug samples at different characteristic x-rays obtained in the energy range from 8 keV to 44 keV from targets viz., Cu, Rb, Mo Ag, Ba and Tb using Am-241 as a primary source of radiation. X-ray intensities were analyzed with and without the attenuator of the each sample using HPGe detector system coupled to multichannel analyzer (MCA) by narrow beam transmission geometry. The obtained mass attenuation coefficient values are compared with the WinXcom values (theoretical). Percentage deviation of WinXCom values and experimental results will signify the quantities of inactive pharmaceutical ingredients are added in the drug samples.en_US
dc.subjectHPGe detector
dc.subjectMass attenuation coefficient
dc.subjectMCA
dc.subjectWinXCom
dc.titleConfirmation of quantity of inactive gradients added in the pharma drugs by determining mass attenuation coefficienten_US
dc.typeArticle
Appears in Collections:1. Journal Articles

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