Evaluation of total phenolic content and free radical scavenging activity of Ficus glomerata roxb

Abstract

In present study attempt has been made to characterize the antioxidant and phenolic content of the traditional medicinal plant Ficus glomerata. Fruit powder was subjected to extraction with methanol, concentrated and lyophilized. Different concentrations of extracts evaluated for their invitro antioxidant potentials using DPPH, ABTS, FRAP, NBTS, TAA tests and total phenolic content also estimated. Total phenolic content observed in this study ranges from 76.77 to 351.45 mg Gallic acid equivalents (GAE)/g. In free radical scavenging assays, Inhibitory Concentration (IC50) of extract ranging from 7.23 mg/ml to 35.08 mg/ml. Correlation studies between phenolic content and free radical scavenging activity and total antioxidants shows the plant phenolics role in their antioxidant capacities. Results indicated that the methanolic extract of F. glomerata fruit is highly effective against free radicals due to rich source of phenolics.