Please use this identifier to cite or link to this item:
http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/3998
Title: | Synthesis and antimicrobial activity of novel 5-substituted-N-(substituted-2H-[1,3]oxazino[6,5-b]quinolin-3(4H)-y1)-3-phenyl-1H-indole-2-carboxamides |
Authors: | Basavarajaiah, SM Mruthyunjayaswamy, BHM |
Keywords: | Indoles quinolines oxazinoquinolines antimicrobial activity |
Issue Date: | 2016 |
Publisher: | NATL INST SCIENCE COMMUNICATION & INFORMATION RESOURCES-NISCAIR |
Citation: | INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY , Vol. 55 , 12 , p. 1511 - 1519 |
Abstract: | (E)-5-Substituted-N-[(1,2-dihydro-substituted-2-oxoquinolin-3-yl)methylene]-3-phenyl-/H-indole-2-carbohydrazides 3a-h, obtained by the reaction of 5-substituted-3-phenyl indole-2-carbohydrazides 1a-b and 1,2-dihydro-substituted-2-oxoquinoline-3-carboxaldehydes 2a-d on further reaction with sodium borohydride followed by treatment with formaldehyde have yielded 5-substituted-N-[(1,2-dihydro-substituted-2-oxoquinoline-3-yl)methy1]-3-phenyl-/H-indole-2-carbohydrazides 4a-h and 5-substituted-N-(substituted-2H-[1,3]oxazino[6,5-b]quinolin-3(4B)-yl)-3-phenyl-/H-indole-2-carboxamides 5a-h respectively. Structures of the all the newly synthesized compounds have been confirmed by spectral data. All-these compounds have been screened for their antibacterial activity against Staphylococcus aureus, Escherichia.; coli, Bacillus substilus, antifungal activity against Aspergillus niger and Candida albicans and anti-tuberculods activity against Mycobacterium tuberculosis (H37R(v)). |
URI: | http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/3998 |
Appears in Collections: | 1. Journal Articles |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.