Synthesis and pharmacological screenings of some N-1-substituted phenyl-N-3-(2 '-substituted indole-3 '-methine) thioureas

Abstract

Various N'-substituted phenyl-N-3-(2'-substituted indole-3'-methine) thioureas were synthesised from respective 2-substituted indole-3-carboxaldehyde and 4-substituted phenylthioureas. The compounds were screened for thier various pharmacological properties, viz., analgesic, anti-inflammatory, oxytocic and anthelmentic activities.