GULBARGA UNIVERSITY, KALABURAGI Institutional Repository
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http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/5071| Title: | SYNTHESIS AND BIOLOGICAL EVALUATION OF 3-ARYL-1-(2-BENZOFURYL)-2-PROPEN-1-ONE ANALOGUES |
| Authors: | Yadav, DB Venkatesh, KB Sangapure, SS |
| Issue Date: | 2009 |
| Publisher: | CONNECT JOURNALS |
| Citation: | INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY , Vol. 19 , 2 , p. 117 - 120 |
| Abstract: | Claisen-Schmidt condensation of 2-acetyl benzofuran 1 with aromatic aldehydes in presence of strong alkali gave 3-aryl-1-(2-benzofuryl)-2-propen-1-ones 2a-c. Reaction of 2a-c with guanidine nitrate in ethanol in presence of sodium hydroxide yielded 2-amino6-aryl-4-(benzofuran-2-yl) pyrimidines 3a-c. The reactions of 3a-c with different reagents furnished compounds 4,5,6 and 7. Newly synthesized compounds were evaluated for their antimicrobial and antiinflammatory activities. |
| URI: | http://gukir.inflibnet.ac.in:8080/jspui/handle/123456789/5071 |
| Appears in Collections: | 1. Journal Articles |
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