Synthetic, spectral, thermal and antimicrobial activity studies of some transition metal complexes derived from 2-hydroxy-methylbenzaldehyde N-(4 '-phenyl-1 ',3 '-thiazol-2 '-yl)semicarbazone

Abstract

The Co-II, Ni-II, Cu-II, Zn-II, Cd-II and Hg-II complexes of Schiff base 2-hydroxy-5-methylbenzaidehyde N-(4'-phenyl-1',3'-thiazol-2'-yl)semicarbazone have been synthesized and characterized by elemental analyses, conductivity measurements, magnetic susceptibility, UV-Visible, IR, NMR, ESR, TGA and Mass spectral data. The Schiff base behaves as tridentate ONO donor ligand and forms the complexes of the type ML stoichiometry for Zn-II, Cd-II and Hg-II complexes and ML2 (metal-ligand) stoichiometry for Co-II, Ni-II and Cu-II, complexes and are non-electrolytic in nature. It is found that Zn-II, Cd-II and Hg-II complexes exhibited tetrahedral geometry whereas Co-II, Ni-II, Cu-II, complexes exhibited octahedral geometry. The ligand and its complexes were tested for their antibacterial activity against Escherichia coli and Staphyloccocus aureus and antifungal activity against Aspergillus niger and Candida albicans.