Biologically active metal complexes containing thiazole core: Synthesis and spectral characterization

Abstract

The present study deals with the synthesis of new ligand N-(4-phenylthiazol-2-yl)-2-(pyridin-2-yl-methylene) hydrazinecarboxamide and it’s Cu (II), Co (II), Ni (II) and Zn (II) complexes and study their antimicrobial activity. The newly prepared compounds are characterized by elemental analysis, FT-IR,1H NMR, mass, UV-visible and ESR spectral techniques. The elemental analysis data and spectral study indicates octahedral geometry for Cu (II), Co (II) and Ni (II) complexes and tetrahedral geometry for Zn (II) complex. All the compounds were tested for antimicrobial activity, the Cu (II) and Co (II) complexes showed good antimicrobial activity. © 2018, Association of Pharmaceutical Teachers of India. All rights reserved.